Effects of Monoamino-Oxidase-A (MAO-A) Inhibition on Skeletal Muscle Inflammation and Wasting through Pancreatic Ductal Adenocarcinoma in Triple Transgenic Mice

Cancer cachexia describes a syndrome of muscle wasting and lipolysis that is still largely untreatable and negatively impacts prognosis, mobility, and healthcare costs. Since upregulation of skeletal muscle monoamine-oxidase-A (MAO-A), a source of reactive oxygen species, may contribute to cachexia,...

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Bibliographic Details

Main Authors:	Schmich, Simon K. P., Keck, Jan, Bonaterra, Gabriel A., Bertoune, Mirjam, Adam, Anna, Wilhelm, Beate, Slater, Emily P., Schwarzbach, Hans, Fendrich, Volker, Kinscherf, Ralf, Hildebrandt, Wulf
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	harmine skeletal muscle atrophy cytokines KPC model E3-ligases pancreatic cancer Medizin cachexia Medical sciences Medicine
Online Access:	PDF Full Text
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