Targeting metabolic rewiring might decrease spread of tumor cells: Mitochondrial tRNA modifications promote cancer metastasis

In a recent study published in Nature, Delaunay and colleagues demonstrate that tRNA modifications in mitochondria have the potential to affect the synthesis of mitochondrial proteins involved in oxidative phosphorylation (OXPHOS), which drives the invasive spread of cancer cells. The inhibition of...

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Bibliographic Details
Main Authors: Luu, Maik, Visekruna, Alexander
Format: Article
Language:English
Published: Philipps-Universität Marburg 2022
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