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TLR7 and IgM: Dangerous Partners in Autoimmunity

The B cell antigen receptor (BCR)-repertoire is capable of recognizing a nearly unlimited number of antigens. Inevitably, the random nature of antibody gene segment rearrangement, needed in order to provide mature B cells, will generate autoreactive specificities. Once tolerance mechanisms fail to b...

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Bibliographic Details
Main Authors: Amendt, Timm, Yu, Philipp
Format: Article
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
autoantibodies
Medizin
autoimmunity
B cells
TLR7
IgM
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2024-02464
Publication Date: 2024-01-10
Source: Erstveröffentlichung: Amendt, T.; Yu, P. TLR7 and IgM: Dangerous Partners in Autoimmunity. Antibodies 2023, 12, 4. https://doi.org/10.3390/antib12010004
Downloads: 68 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0246
https://doi.org/10.3390/antib12010004

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