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Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones

Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the transcriptomic landscape to sustain its own replicatio...

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Main Authors: Herbel, Stefanie M., Moyon, Lambert, Christ, Marvin, Elsayed, Eslam M., Caffrey, Brian E., Malmsheimer, Silke, Grin, Iwan, Hoffmann, Kerstin, Surmann, Kristin, Blankenburg, Sascha, Jung, Anna Lena, Herkt, Christina E., Borsò, Marco, Bozdag, Beyza, Imhof, Axel, Becker, Anke, Wagner, Samuel, Bange, Gert, Völker, Uwe, Bertrams, Wilhelm, Marsico, Annalisa, Schmeck, Bernd
Format: Article
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
Infection
Smh1
Legionella pneumophila
macrophage
histone-deacetylase
Medizin
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2023-01555
Publication Date: 2023-10-04
Source: Erstveröffentlichung: Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico & Bernd Schmeck (2022) Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones, Virulence, 13:1, 2042-2058, DOI: 10.1080/21505594.2022.2149973
Downloads: 4 (2025), 47 (2024), 9 (2023)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2023/0155
https://doi.org/10.1080/21505594.2022.2149973

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