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The iron–sulfur cluster assembly (ISC) protein Iba57 executes a tetrahydrofolate-independent function in mitochondrial [4Fe–4S] protein maturation

Mitochondria harbor the bacteria-inherited iron–sulfur cluster assembly (ISC) machinery to generate [2Fe–2S; iron–sulfur (Fe–S)] and [4Fe–4S] proteins. In yeast, assembly of [4Fe–4S] proteins specifically involves the ISC proteins Isa1, Isa2, Iba57, Bol3, and Nfu1. Functional defects in their human...

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Bibliographic Details
Main Authors: Mühlenhoff, Ulrich, Weiler, Benjamin Dennis, Nadler, Franziska, Millar, Robert, Kothe, Isabell, Freibert, Sven-Andreas, Altegoer, Florian, Bange, Gert, Lill, Roland
Format: Article
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
mitochondrial disease
Medizin
crystallography
mitochondria
iron–sulfur cluster assembly
folate
iron–sulfur protein
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2023-01499
Publication Date: 2023-10-04
Source: Erstveröffentlichung: Mühlenhoff, Ulrich; Weiler, Benjamin Dennis; Nadler, Franziska; Millar, Robert; Kothe, Isabell; Freibert, Sven-Andreas et al. (2022): The iron–sulfur cluster assembly (ISC
Downloads: 55 (2024), 10 (2023)
License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Access URL: https://archiv.ub.uni-marburg.de/es/2023/0149
https://doi.org/10.1016/j.jbc.2022.102465.

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