Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II

Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II

Hypoxia stabilizes the transcription factor HIF-1α, which promotes the transcription of many genes essential to adapt to reduced oxygen levels. Besides proline hydroxylation, expression of HIF-1α is also regulated by a range of other posttranslational modifications including phosphorylation by cAMP-...

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Bibliographic Details
Main Authors: Seaayfan, Elie, Nasrah, Sadiq, Quell, Lea, Radi, Aline, Kleim, Maja, Schermuly, Ralph T., Weber, Stefanie, Laghmani, Kamel, Kömhoff, Martin
Format: Article
Language:English
Published: Philipps-Universität Marburg 2022
Subjects:
Medizin
HIF-1α
GalphaS
MAGED2
Bartter
hypoxia
PKA type II
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2023-01374
Publication Date: 2023-09-04
Source: Erstveröffentlichung: Seaayfan, E.; Nasrah, S.; Quell, L.; Radi, A.; Kleim, M.; Schermuly, R.T.; Weber, S.; Laghmani, K.; Kömhoff, M. Reciprocal Regulation of MAGED2 and HIF-1α Augments Their Expression under Hypoxia: Role of cAMP and PKA Type II. Cells 2022, 11, 3424. https://doi.org/10.3390/cells11213424
Downloads: 51 (2024), 14 (2023)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2023/0137
https://doi.org/10.3390/cells11213424

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