Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...

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Bibliographic Details

Main Authors:	Sungur, A. Özge, Zeitouny, Caroline, Gabele, Lea, Metz, Isabell, Wöhr, Markus, Michaelsen-Preusse, Kristin, Rust, Marco B.
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	object recognition memory formation actin dynamics Medizin social recognition spine morphology ultrasonic vocalization Medical sciences Medicine
Online Access:	PDF Full Text
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