Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...

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Bibliographic Details
Main Authors: Sungur, A. Özge, Zeitouny, Caroline, Gabele, Lea, Metz, Isabell, Wöhr, Markus, Michaelsen-Preusse, Kristin, Rust, Marco B.
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
object recognition
memory formation
actin dynamics
Medizin
social recognition
spine morphology
ultrasonic vocalization
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2023-00387
Publication Date: 2023-04-03
Source: Erstveröffentlichung: Sungur AÖ, Zeitouny C, Gabele L, Metz I, Wöhr M, Michaelsen-Preusse K and Rust MB (2022) Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits. Front. Mol. Neurosci. 15:952782. doi: https://doi.org/10.3389/fnmol.2022.952782
Downloads: 40 (2024), 21 (2023)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2023/0038
https://doi.org/10.3389/fnmol.2022.952782

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