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Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance

Hypoxia, an oxygen-deprived condition of the tumor, is one of the major reasons for resistance to chemotherapy. Carbonic anhydrases are generally involved in pH homeostasis in normal conditions, but in solid tumors having a strong relation with hypoxia, the car...

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Bibliographic Details
Main Authors: Amin, Muhammad Umair, Ali, Sajid, Alie, Muhammad Yasir, Fuhrmann, Dominik C., Tarik, Imran, Seitz, Benjamin S., Preis, Eduard, Büßler, Jana, Brüne, Bernhard, Bakowsky, Udo
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
liposomes
Pharmakologie, Therapeutik
Hypoxia
mesoporous silica nanoparticles
CA-IX enzyme inhibition
co-delivery
Pharmacology & therapeutics, prescription drugs
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Call Number: urn:nbn:de:hebis:04-es2023-00309
Publication Date: 2023-04-03
Source: Erstveröffentlichung: Muhammad Umair Amin, Sajid Ali, Muhammad Yasir Ali, Dominik C. Fuhrmann, Imran Tariq, Benjamin S. Seitz, Eduard Preis, Jana Brüßler, Bernhard Brüne & Udo Bakowsky (2022) Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance, Drug Delivery, 29:1, 2072-2085, https://doi.org/10.1080/10717544.2022.2092234
Downloads: 6 (2025), 57 (2024), 46 (2023)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2023/0030
https://doi.org/10.1080/10717544.2022.2092234

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