Effects of Receptor Specificity and Conformational Stability of Influenza A Virus Hemagglutinin on Infection and Activation of Different Cell Types in Human PBMCs

Humans can be infected by zoonotic avian, pandemic and seasonal influenza A viruses (IAVs), which differ by receptor specificity and conformational stability of their envelope glycoprotein hemagglutinin (HA). It was shown that receptor specificity of the HA determines the tropism of IAVs to human...

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Main Authors: Dorna, Jens, Kaufmann, Andreas, Bockmann, Viktoria, Raifer, Hartmann, West, Johanna, Matrosovich, Mikhail, Bauer, Stefan
Format: Article
Language:German
Published: Philipps-Universität Marburg 2022
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Call Number: urn:nbn:de:hebis:04-es2022-01633
Publication Date: 2022-11-22
Source: Erstveröffentlichung: Dorna J, Kaufmann A, Bockmann V, Raifer H, West J, Matrosovich M and Bauer S (2022) Effects of Receptor Specificity and Conformational Stability of Influenza A Virus Hemagglutinin on Infection and Activation of Different Cell Types in Human PBMCs. Front. Immunol. 13:827760. https://doi.org/10.3389/fimmu.2022.827760
Downloads: 26 (2024), 71 (2023), 3 (2022)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2022/0163
https://doi.org/10.3389/fimmu.2022.827760