Toward Novel [18F]Fluorine-labeled Radiotracers for the Imaging of α-Synuclein Fibrils

The accumulation of α-synuclein aggregates (α-syn) in the human brain is an occurrence common to all α-synucleinopathies. Non-invasive detection of these aggregates in a living brain with a target-specific radiotracer is not yet possible. We have recently discovered that the inclusion of a methylene...

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Bibliographic Details

Main Authors:	Uzuegbunam, Bright C., Li, Junhao, Paslawsk, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Yousefi, Behrooz Hooshyar
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2022
Subjects:	PET tracer development α-synuclein aggregates disaryl Medizin positron emission tomography (PET) ruthenium-mediated deoxyfluorination α-synucleinopathies Medical sciences Medicine
Online Access:	PDF Full Text
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