Showing 1 - 20 results of 65 for search 'Klebe, Gerhard (Prof.)', query time: 0.04s Refine Results
  1. 1
    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design
    by Badran, Mohammed
    Published 2021
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  2. 2
    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase
    by Nguyen, Andreas
    Published 2020
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  3. 3
    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A
    by Oebbeke, Matthias
    Published 2021
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  4. 4
    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme
    by Nguyen, Dzung
    Published 2020
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  5. 5
    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II
    by Glöckner, Steffen
    Published 2020
    Contributors: “...Klebe, Gerhard Prof. Dr....”
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  6. 6
    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.
    by Hassaan, Engi
    Published 2019
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  7. 7
    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag zur Darstellung von Inhibitoren der Aldose-Reduktase und Carboanhydrase II
    by Ngo, Trong Khang
    Published 2020
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  8. 8
    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery
    by Petrick, Joy Kristin
    Published 2019
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  9. 9
    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery
    by Münzker Lena
    Published 2019
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  10. 10
    The Power of Fragments: FBLD approach to investigate protein structures
    by Magari, Francesca
    Published 2020
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  11. 11
    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana
    by Müller, Daniela
    Published 2019
    Contributors: “...Klebe, Gerhard (Prof. Dr. rer. nat.)...”
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  12. 12
    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Ligand Complexes
    by Hüfner, Tobias
    Published 2019
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  13. 13
    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography
    by Siefker, Christof
    Published 2018
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  14. 14
    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin
    by Cramer, Jonathan
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  15. 15
    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques
    by Bertoletti, Nicole
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  16. 16
    Beyond Affinity: Drug-Kinase Interaction Put under the Microscope
    by Wienen-Schmidt, Barbara
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof.)...”
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  17. 17
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns
    by Terwesten, Felix
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  18. 18
    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A
    by Müller, Janis
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  19. 19
    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study
    by Krimmer, Stefan Günter
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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  20. 20
    17β Hydroxysteroid Dehydrogenase 14 (17β-HSD14): Entwicklung und Synthese potenter und selektiver Inhibitoren zur strukturellen Charakterisierung und Untersuchung der physiologischen Rolle des Enzyms
    by Braun, Florian
    Published 2017
    Contributors: “...Klebe, Gerhard (Prof. Dr.)...”
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