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Titel:Veränderung der Messergebnisse der quantitativen Ultrasonometrie (QUS) am Os calcaneusim Verlaufe der Schwangerschaft
Autor:Hahn, Birgit Renate Lieselotte
Weitere Beteiligte: Hadji, Peyman (Prof. Dr. med.)
Veröffentlicht:2016
URI:https://archiv.ub.uni-marburg.de/diss/z2017/0008
URN: urn:nbn:de:hebis:04-z2017-00081
DOI: https://doi.org/10.17192/z2017.0008
DDC: Medizin, Gesundheit
Titel(trans.):Changes of measurements of quantitative ultrasonometry (QUS)in the calcaneal bone during pregnancy
Publikationsdatum:2017-01-17
Lizenz:https://creativecommons.org/licenses/by/4.0

Dokument

Schlagwörter:
Bone Mass Loss, Osteoporosis, Osteoporose, Knochenstoffwechsel, Pregnancy, Knochendichteminderung, Schwangerschaft

Zusammenfassung:
Die vorliegende Studie konnte einen signifikanten Abfall des T-Score und Steifigkeitsindexes (SI) im Verlauf der Schwangerschaft vom zweiten zum dritten Trimester nachweisen. Dies geht einher mit einem erhöhten Bedarf an Kalzium und folgendem Verlust an Knochendichte (BMD) während der Hochphase fetalen Wachstums am Ende der Schwangerschaft. Junge Primiparae ohne anamnestische körperliche Betätigung zeigten dabei Ultraschallmesswerte, die auf das höchste Risiko für Knochenfrakturen hindeuteten. Eine mögliche spätere Normalisierung der Messwerte weist dabei auf mögliche molekulare und biochemische Mechanismen hin, die Gegenstand weiteren Untersuchungen bleiben müssen.

Summary:
A significant decrease of QUS - t-score and SI variables from the second to third trimester of pregnancy could be shown in this study. An increasing demand of calcium and loss of bone mass density (BMD) during the phase of maximum fetal growth rate at the end of pregnancy correlates with this. Ultrasoundmeasurements showed levels for the highest risk for bonefractures during pregnancy in young primiparae without any prior bodily exercise during adolescence. Eventual later return to average-level measurements indicating bone-recovery may be caused by molecular and biochemical mechanisms as yet to be left to further investigations.

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