Towards the Extension of the Substrate Spectrum of the [Fe]-Hydrogenase Hmd

Towards the Extension of the Substrate Spectrum of the [Fe]-Hydrogenase Hmd

In hydrogenotrophic methanogenesis, methenyl-tetrahydromethanopterin (methenyl H4MPT+) is sequentially reduced to methylene-H4MPT and methyl H4MPT. The H2-forming methylene H4MPT dehydrogenase Hmd catalyzes the reduction of methenyl H4MPT+ to methylene H4MPT using H2 as electron donor. The reduction...

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Bibliografiska uppgifter
Huvudupphovsman: Gehl, Manuel
Övriga upphovsmän: Shima, Seigo (Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2023
Ämnen:
methylene-tetrahydrofolate reductase
crystal structure
[Fe]-hydrogenase
katalytischer Mechanismus
Methylen-Tetrahydrofolat-Reduktase
Methylen-Tetrahydromethanopterin-Reduktase
evolution
Evolution
catalytic mechanism
methylene-tetrahydromethanopterin reductase
[Fe]-hydrogenas
Kristallstruktur
Biowissenschaften, Biologie
[Fe]-Hydrogena
Life sciences
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