Identifizierung funktioneller Untereinheiten des Transkriptionsfaktors interferon regulatory factor 4

Identifizierung funktioneller Untereinheiten des Transkriptionsfaktors interferon regulatory factor 4

Interferon regulatory factor 4 is a crucial factor in adaptive immunity in both T and B cell mediated processes. Knockout mice lacking IRF4 show severe defects in developing functional T cell subsets, including Th2, Th9 and Th17, as well as B cells arrested in early development stages, which l...

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Autore principale: Staudenraus, Daniel
Altri autori: Lohoff, Michael (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2022
Soggetti:
Biowissenschaften, Biologie
Immunologie
T cell differentiation
Punktmutation
Differenzierung
IRF4
Immunology
T-Zelldifferenzierung
Life sciences
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