Publikationsserver
Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase
The design and development of a drug is complex and usually extends over many years. Different approaches can facilitate lead optimization. This work focuses on specific aspects that could lead to advances in drug discovery. After an introduction to drug design and the two studied target proteins,...
में बचाया:
| मुख्य लेखक: | |
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| अन्य लेखक: | |
| स्वरूप: | Dissertation |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
Philipps-Universität Marburg
2022
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| विषय: | |
| ऑनलाइन पहुंच: | पीडीएफ पूर्ण पाठ |
| टैग: |
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इंटरनेट
पीडीएफ पूर्ण पाठ| बोधानक: |
urn:nbn:de:hebis:04-z2022-01182 |
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| प्रकाशन तिथि: |
2022-05-25 |
| Datum der Annahme: |
2022-04-12 |
| Downloads: |
95 (2024), 132 (2023), 40 (2022) |
| Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
| यूआरएल में प्रवेश करें: |
https://archiv.ub.uni-marburg.de/diss/z2022/0118 https://doi.org/10.17192/z2022.0118 |