Structural and functional analysis of non-canonical tandem-thioesterases

Structural and functional analysis of non-canonical tandem-thioesterases

Nonribosomal peptide synthetases (NRPS) are known to produce a diverse range of bioactive natural products, like antibiotics, immunosuppressants or cytostatics. These pharmacologically important properties have attracted increased scientific interest, on the one hand to advance the discovery of new...

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Autore principale: Biermeier, Maximilian
Altri autori: Essen, Lars-Oliver (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2021
Soggetti:
Kristallstruktur
NRPS
nonribosomal peptidsynthetase
Chemie
terminationmodul
Inhibitor-Assay
tandem-Te
Tandem-Te
Terminationsmodul
crystal structure
tandem-TE
termination domain
Nichtribosomale Peptidsynthetasen
Terminationsdomäne
Tandem-Thioesterase
inhibitor-assay
Chemistry & allied sciences
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