Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

Badran, Mohammed

Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

The first topic of this thesis (Chapter 2) presents a mutational study performed on 17β-hydroxysteroid dehydrogenase type 14 (17β-HSD14) S205 variant. Five different mutations were done with respect to five amino acids which are believed to have an essential role in the enzyme activity and assembly....

Ful tanımlama

Kaydedildi:

Detaylı Bibliyografya
Yazar:	Badran, Mohammed
Diğer Yazarlar:	Klebe, Gerhard (Prof. Dr.) (Tez danışmanı)
Materyal Türü:	Dissertation
Dil:	İngilizce
Baskı/Yayın Bilgisi:	Philipps-Universität Marburg 2021
Konular:	Biowissenschaften, Biologie Inhibitoren im Komplex mit dem Protein Strukturbestimmung Kristallstrukturen 17b-HSD14 Fragment Screening crystallography, Inhibitor-Protein com Life sciences
Online Erişim:	PDF Tam Metin
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

İlk yorumlayan siz olun!

Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

Benzer Materyaller