Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

The first topic of this thesis (Chapter 2) presents a mutational study performed on 17β-hydroxysteroid dehydrogenase type 14 (17β-HSD14) S205 variant. Five different mutations were done with respect to five amino acids which are believed to have an essential role in the enzyme activity and assembly....

詳細記述

保存先:
書誌詳細
第一著者: Badran, Mohammed
その他の著者: Klebe, Gerhard (Prof. Dr.) (論文の指導者)
フォーマット: Dissertation
言語:英語
出版事項: Philipps-Universität Marburg 2021
主題:
オンライン・アクセス:PDFフルテキスト
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!