Selective cellular vulnerability and pathology progression patterns in two mouse models of Parkinson’s disease

Selective cellular vulnerability and pathology progression patterns in two mouse models of Parkinson’s disease

Parkinson's disease is a highly debilitating disorder classically characterized by the degeneration of dopaminergic midbrain neurons of the substantia nigra. The resulting nigrostriatal dopamine deficiency is thought to be responsible for the onset of the cardinal Parkinson's motor symptom...

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Bibliografski detalji
Glavni autor: Geibl, Fanni Fruzsina
Daljnji autori: Oertel, Wolfgang H. (Prof. Dr. med. Dr. h.c.) (Savjetnik disertacije)
Format: Dissertation
Jezik:engleski
Izdano: Philipps-Universität Marburg 2019
Teme:
adeno-associated viral vectors
alpha-Synuclein
Parkinson's disease
Medizin
Parkinson-Krankheit
alpha-synuclein
selektive Vulnerabilit
Locus coeruleus
selective vulnerab
Pedunculopontiner Kern
pedunculopontine nucleus
adeno-assoziierte Viren
preformed fibrils
präformierte Fibrillen
Medical sciences Medicine
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Detalji primjeraka od
Signatura: urn:nbn:de:hebis:04-z2019-04237
Datum izdanja: 2020-05-25
Datum der Annahme: 2019-10-09
Downloads: 29 (2024), 68 (2023), 74 (2022), 45 (2021), 22 (2020)
Lizenz: https://creativecommons.org/licenses/by-nc-nd/4.0/
URL pristupa: https://archiv.ub.uni-marburg.de/diss/z2019/0423
https://doi.org/10.17192/z2019.0423

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