Selective cellular vulnerability and pathology progression patterns in two mouse models of Parkinson’s disease

Selective cellular vulnerability and pathology progression patterns in two mouse models of Parkinson’s disease

Parkinson's disease is a highly debilitating disorder classically characterized by the degeneration of dopaminergic midbrain neurons of the substantia nigra. The resulting nigrostriatal dopamine deficiency is thought to be responsible for the onset of the cardinal Parkinson's motor symptom...

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Autor principal: Geibl, Fanni Fruzsina
Altres autors: Oertel, Wolfgang H. (Prof. Dr. med. Dr. h.c.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2019
Matèries:
adeno-associated viral vectors
alpha-Synuclein
Parkinson's disease
Medizin
Parkinson-Krankheit
alpha-synuclein
selektive Vulnerabilit
Locus coeruleus
selective vulnerab
Pedunculopontiner Kern
pedunculopontine nucleus
adeno-assoziierte Viren
preformed fibrils
präformierte Fibrillen
Medical sciences Medicine
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Signatura: urn:nbn:de:hebis:04-z2019-04237
Data de publicació: 2020-05-25
Datum der Annahme: 2019-10-09
Downloads: 29 (2024), 68 (2023), 74 (2022), 45 (2021), 22 (2020)
Lizenz: https://creativecommons.org/licenses/by-nc-nd/4.0/
URL d'accés: https://archiv.ub.uni-marburg.de/diss/z2019/0423
https://doi.org/10.17192/z2019.0423

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