Establishment of new experimental models of progressive prodromal Parkinson’s disease using viral-mediated overexpression of wild-type human α-synuclein in the substantia nigra compacta and the locus coeruleus in mice

Lee, Bolam

Establishment of new experimental models of progressive prodromal Parkinson’s disease using viral-mediated overexpression of wild-type human α-synuclein in the substantia nigra compacta and the locus coeruleus in mice

Part 1. Summary Alpha-7-nicotine-acetylcholine-receptor (α7-nAChR) agonists modulate the cholinergic anti-inflammatory pathway to attenuate proinflammatory signals and reduce dopaminergic neuronal cell loss in toxin-induced experimental murine models of Parkinson’s disease (PD). However, no researc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
1. Verfasser:	Lee, Bolam
Beteiligte:	Oertel, Wolfgang (Prof. Dr. Dr.) (BetreuerIn (Doktorarbeit))
Format:	Dissertation
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2019
Schlagworte:	α-Synuclein Parkinsonkrankheit Medizin Medical sciences Medicine
Online Zugang:	PDF-Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!

Establishment of new experimental models of progressive prodromal Parkinson’s disease using viral-mediated overexpression of wild-type human α-synuclein in the substantia nigra compacta and the locus coeruleus in mice

Ähnliche Einträge