Elucidating the functional role of Dual-specificity Tyrosine Regulated Kinase 1B (DYRK1B) in the Hedgehog (Hh) Signaling Pathway.

Elucidating the functional role of Dual-specificity Tyrosine Regulated Kinase 1B (DYRK1B) in the Hedgehog (Hh) Signaling Pathway.

Hedgehog signaling (Hh) plays a crucial role in vital processes such as embryonic development or cell homeostasis. Aberrant Hh signaling is linked to formation, progression, and growth of tumors. The canonical Hh signaling cascade is initiated by binding of the Hh ligand to its receptor Patched1...

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Bibliografiska uppgifter
Huvudupphovsman: Singh, Rajeev
Övriga upphovsmän: Lauth, Matthias (PD Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2018
Ämnen:
Oncology
DYRK Kinase
Tumor Signalwege
Molecular biology
Hedgehog Pathway
Molekularbiologie
Medizin
Tumor Signaling Pathways
Medical sciences Medicine
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