Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

The primary aim of this thesis was the crystallographic analysis of PKA and Pim1 crystals in complex with small fragment-like molecules to identify potential fragment binders in the protein kinase binding pockets. In the first subproject of this thesis, the similarities and differences between both...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Siefker, Christof
Beste egile batzuk: Klebe, Gerhard (Prof. Dr.) (Tesi aholkularia)
Formatua: Dissertation
Hizkuntza:ingelesa
Argitaratua: Philipps-Universität Marburg 2018
Gaiak:
Sarrera elektronikoa:PDF testu osoa
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!