17β Hydroxysteroid Dehydrogenase 14 (17β-HSD14): Entwicklung und Synthese potenter und selektiver Inhibitoren zur strukturellen Charakterisierung und Untersuchung der physiologischen Rolle des Enzyms

In dieser Arbeit wird die Familie der 17β-Hydroxysteroid Dehydrogenasen (17β-HSDs) vorgestellt, die in vitro die Oxidation und/oder Reduktion von Steroidhormonen in Position 17 des Steroidgerüstes katalysieren. 17β-HSDs besitzen die Fähigkeit lokale Konzentrationen von aktiven und inaktiven Hormonde...

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Bibliographic Details
Main Author: Braun, Florian
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2017
Pharmazeutische Chemie
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Call Number: urn:nbn:de:hebis:04-z2017-06752
Downloads: 6 (2020), 46 (2019), 39 (2018), 5 (2017)
Publication Date: 2017-10-25
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2017/0675
https://doi.org/10.17192/z2017.0675