Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells

Opposing activities of IRF1 and IRF4 in regulating the Il9 locus in Th9 cells

The T helper (Th)9 cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Positive regulators including interferon regulatory factor (IRF)4 promote expression of the key cytokine interleukin (IL)-9 in Th9 cells, whereas interferon (IFN)-γ r...

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Autore principale: Campos Carrascosa, Lucia
Altri autori: Huber, Magdalena (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2017
Soggetti:
Il9-Locus
IRF4
IRF1
Th9-Zellen
Medizin
Il9 locus
Th9 cells
Medical sciences Medicine
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