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Beyond Affinity: Drug-Kinase Interaction Put under the Microscope
Over the last 20 years, the consideration of biophysical parameters such as kinetics and thermodynamics has been used to guide modern drug design. In contrast to the classical approach that mainly relies on affinity optimization, biophysical parameters allow a further discrimination of potential dru...
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| 主要作者: | |
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| 其他作者: | |
| 格式: | Dissertation |
| 語言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2017
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| 主題: | |
| 在線閱讀: | PDF-Volltext |
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PDF-Volltext| 索引號: |
urn:nbn:de:hebis:04-z2017-05379 |
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| Publikationsdatum: |
2018-04-05 |
| Datum der Annahme: |
2017-06-12 |
| Downloads: |
86 (2024), 97 (2023), 38 (2022), 13 (2021), 17 (2020), 24 (2019), 17 (2018) |
| Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
| Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2017/0537 https://doi.org/10.17192/z2017.0537 |