Beyond Affinity: Drug-Kinase Interaction Put under the Microscope
Over the last 20 years, the consideration of biophysical parameters such as kinetics and thermodynamics has been used to guide modern drug design. In contrast to the classical approach that mainly relies on affinity optimization, biophysical parameters allow a further discrimination of potential dru...
Wedi'i Gadw mewn:
Prif Awdur: | |
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Awduron Eraill: | |
Fformat: | Dissertation |
Iaith: | Saesneg |
Cyhoeddwyd: |
Philipps-Universität Marburg
2017
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Pynciau: | |
Mynediad Ar-lein: | Testun PDF llawn |
Tagiau: |
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Rhyngrwyd
Testun PDF llawnRhif Galw: |
urn:nbn:de:hebis:04-z2017-05379 |
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Dyddiad Cyhoeddi: |
2018-04-05 |
Datum der Annahme: |
2017-06-12 |
Downloads: |
88 (2024), 97 (2023), 38 (2022), 13 (2021), 17 (2020), 24 (2019), 17 (2018) |
Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
URL mynediad: |
https://archiv.ub.uni-marburg.de/diss/z2017/0537 https://doi.org/10.17192/z2017.0537 |