Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members

Cancer development is a multistep process which leads to tumors composed of diverse cell populations originating from one cell which underwent differential genetic changes over time. Within one tumor, such heterogeneity provides distinct subpopulations with selection advantages promoting metastasis...

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Bibliographic Details
Main Author: Fuchs, Jeannette
Contributors: Stiewe, Thorsten (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2016
Molekularbiologie und Tumorforschung
Online Access:PDF Full Text
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