Characterization of cellular and humoral immune responses in pemphigus patients and an HLA-transgenic mouse model

The rare, but potentially fatal autoimmune disorder pemphigus is considered as a prototypical antibody-mediated organ-specific disease, in which immunoglobulin (Ig) G autoantibodies (auto-ab) mainly target the desmosomal cadherins Desmoglein 3 (Dsg3) and Dsg1 within the epidermis. This process, refe...

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Bibliographic Details
Main Author: Hennerici, Tina
Contributors: Eming, Rüdiger (PD Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2016
Online Access:PDF Full Text
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