Structure-Based Design of a Blood Coagulation Factor XIII Blocker

Structure-Based Design of a Blood Coagulation Factor XIII Blocker

FXIII belongs to the family of transglutaminases, mainly catalyzing the cross-linking of proteins by formation of an isopetide bond between a glutamine and a lysine side chain. FXIII represents the last enzyme of the blood coagulation cascade providing final stability to the blood clot by cross-link...

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Bibliografiska uppgifter
Huvudupphovsman: Stieler, Martin
Övriga upphovsmän: Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:tyska
Publicerad: Philipps-Universität Marburg 2017
Ämnen:
Antikoagulans
Medizinische Chemie
Transglutaminases
Pharmakologie, Therapeutik
Blutgerinnung
Faktor XIII
Blood Coagulation
Factor XIII
Medical Chemistry
Transglutaminasen
Anticoagulants
Pharmacology & therapeutics, prescription drugs
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