Structure-Based Design of a Blood Coagulation Factor XIII Blocker

Structure-Based Design of a Blood Coagulation Factor XIII Blocker

FXIII belongs to the family of transglutaminases, mainly catalyzing the cross-linking of proteins by formation of an isopetide bond between a glutamine and a lysine side chain. FXIII represents the last enzyme of the blood coagulation cascade providing final stability to the blood clot by cross-link...

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Bibliografski detalji
Glavni autor: Stieler, Martin
Daljnji autori: Klebe, Gerhard (Prof. Dr.) (Savjetnik disertacije)
Format: Dissertation
Jezik:German
Izdano: Philipps-Universität Marburg 2017
Teme:
Antikoagulans
Medizinische Chemie
Transglutaminases
Pharmakologie, Therapeutik
Blutgerinnung
Faktor XIII
Blood Coagulation
Factor XIII
Medical Chemistry
Transglutaminasen
Anticoagulants
Pharmacology & therapeutics, prescription drugs
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