Structure-Based Design of a Blood Coagulation Factor XIII Blocker

Structure-Based Design of a Blood Coagulation Factor XIII Blocker

FXIII belongs to the family of transglutaminases, mainly catalyzing the cross-linking of proteins by formation of an isopetide bond between a glutamine and a lysine side chain. FXIII represents the last enzyme of the blood coagulation cascade providing final stability to the blood clot by cross-link...

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Autor principal: Stieler, Martin
Otros Autores: Klebe, Gerhard (Prof. Dr.) (Orientador)
Formato: Dissertation
Lenguaje:alemán
Publicado: Philipps-Universität Marburg 2017
Materias:
Antikoagulans
Medizinische Chemie
Transglutaminases
Pharmakologie, Therapeutik
Blutgerinnung
Faktor XIII
Blood Coagulation
Factor XIII
Medical Chemistry
Transglutaminasen
Anticoagulants
Pharmacology & therapeutics, prescription drugs
Acceso en línea:Texto Completo PDF
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