Structure-Based Design of a Blood Coagulation Factor XIII Blocker
FXIII belongs to the family of transglutaminases, mainly catalyzing the cross-linking of proteins by formation of an isopetide bond between a glutamine and a lysine side chain. FXIII represents the last enzyme of the blood coagulation cascade providing final stability to the blood clot by cross-link...
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Format: | Dissertation |
Sprog: | German |
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Philipps-Universität Marburg
2017
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