Dissection of Complex Genetic Correlations into Interaction Effects

Dissection of Complex Genetic Correlations into Interaction Effects

Living systems are overwhelmingly complex and consist of many interacting parts. Already the quantitative characterization of a single human cell type on genetic level requires at least the measurement of 20000 gene expressions. It remains a big challenge for theoretical approaches to discover patte...

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Bibliografische gegevens
Hoofdauteur: Grau, Michael
Andere auteurs: Lenz, Peter (Prof. Dr.) (Thesis begeleider)
Formaat: Dissertation
Taal:Engels
Gepubliceerd in: Philipps-Universität Marburg 2015
Onderwerpen:
Tumorklassifikation
Genexpression
Hochdimensionale Daten
Genanalyse
complex systems
Grenzen der Hauptkomponentenanalyse
Physik
survival prediction
Nichtlineares Regressionsmodell
tumor classification
interpretable high-dimensional laws of interaction
interpretierbare hochdimensionale Interaktionsvorschriften
Überlebensprädiktion
Komplexes System
signal dissection
Maschinelles Lernen
Physics
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