Bewegungskontrolle der Handmotorik bei Patienten mit Asperger Autismus

Einleitung: Patienten, die an einer Autismus-Spektrum-Störung leiden, weisen häufig motorische Defizite unterschiedlichen Ausmaßes auf. Es ist unklar, welche Pathophysiologie und welche Hirnsysteme für diese Bewegungsstörungen verantwortlich sind. Post-mortem Untersuchungen, strukturelle und funktio...

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Main Author: Riegg, Florian
Contributors: Dodel, Richard (Prof. Dr. med.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2016
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1. Johnson-Greene, D., K. M. Adams, et al. (1997). "Impaired upper limb coordination in alcoholic cerebellar degeneration." Arch Neurol 54(4): 436-439.

2. Bailey, A., P. Luthert, et al. (1998). "A clinicopathological study of autism." Brain 121 ( Pt 5): 889-905.

3. Palmen, S. J., H. van Engeland, et al. (2004). "Neuropathological findings in autism." Brain 127(Pt 12): 2572-2583.

4. Ilg, W., M. A. Giese, et al. (2008). "The influence of focal cerebellar lesions on the control and adaptation of gait." Brain 131(Pt 11): 2913-2927.

5. Jeannerod, M., Y. Paulignan, et al. (1998). "Grasping an object: one movement, several components." Novartis Foundation symposium 218: 5-16; discussion 16-20.

6. Bastian, A. J. and W. T. Thach (1995). "Cerebellar outflow lesions: a comparison of movement deficits resulting from lesions at the levels of the cerebellum and thalamus." Ann Neurol 38(6): 881-892.

7. Vingerhoets, F. J., M. Schulzer, et al. (1997). "Which clinical sign of Parkinson's disease best reflects the nigrostriatal lesion?" Ann Neurol 41(1): 58-64.

8. Fellows, S. J. and J. Noth (2004). "Grip force abnormalities in de novo Parkinson's disease." Movement Disorders 19(5): 560-565.

9. Rizzolatti, G., L. Fadiga, et al. (1996). "Localization of grasp representations in humans by PET: 1. Observation versus execution." Exp Brain Res 111(2): 246-252.

10. Flanagan, J. R. and A. M. Wing (1993). "Modulation of grip force with load force during point- to-point arm movements." Exp Brain Res 95(1): 131-143.

11. Kohen-Raz, R., F. R. Volkmar, et al. (1992). "Postural control in children with autism." J Autism Dev Disord 22(3): 419-432.

12. Asperger, H. (1944). Die "Autistischen Psychopathen" im Kindesalter. Archiv für Psychiatrie und Nervenkrankheiten 117. Wien: 76-136.

13. Manjiviona, J. and M. Prior (1995). "Comparison of Asperger syndrome and high-functioning autistic children on a test of motor impairment." J Autism Dev Disord 25(1): 23-39.

14. Rand, M. K., Y. Shimansky, et al. (2000). "Effects of accuracy constraints on reach-to-grasp movements in cerebellar patients." Exp Brain Res 135(2): 179-188.

15. Serrien, D. J. and M. Wiesendanger (1999). "Grip-load force coordination in cerebellar patients." Exp Brain Res 128(1-2): 76-80.

16. Marteniuk, R. G., J. L. Leavitt, et al. (1990). "Functional relationships between grasp and transport components in a prehension task." Human Movement Science 9(2): 149-176.

17. Rost, K., D. A. Nowak, et al. (2005). "Preserved and impaired aspects of predictive grip force control in cerebellar patients." Clin Neurophysiol 116(6): 1405-1414.

18. Stanfield, A. C., A. M. McIntosh, et al. (2008). "Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies." Eur Psychiatry 23(4): 289-299.

19. Miall, R. C. and L. O. D. Christensen (2004). "The effect of rTMS over the cerebellum in normal human volunteers on peg-board movement performance." Neurosci Lett 371(2–3): 185-189.

20. Küper, M., J. Hermsdörfer, et al. (2011). "Lesions of the dentate and interposed nuclei are associated with impaired prehension in cerebellar patients." Neurosci Lett 499(2): 132- 136.

21. Kuhn, S., A. Romanowski, et al. (2012). "Manual dexterity correlating with right lobule VI volume in right-handed 14-year-olds." Neuroimage 59(2): 1615-1621.

22. Imazu, S., T. Sugio, et al. (2007). "Differences between actual and imagined usage of chopsticks: an fMRI study." Cortex 43(3): 301-307.

23. Kawato, M., T. Kuroda, et al. (2003). "Internal forward models in the cerebellum: fMRI study on grip force and load force coupling." Prog Brain Res 142: 171-188.

24. Fellows, S. J., J. Ernst, et al. (2001). "Precision grip deficits in cerebellar disorders in man." Clin Neurophysiol 112(10): 1793-1802.

25. Osu, R., Y. Uno, et al. (1997). "Possible explanations for trajectory curvature in multijoint arm movements." J Exp Psychol Hum Percept Perform 23(3): 890-913.

26. Costa, L. D., H. G. Vaughan, Jr., et al. (1963). "Purdue Pegboard as a predictor of the presence and laterality of cerebral lesions." J Consult Psychol 27: 133-137.

27. Courchesne, E., R. Yeung-Courchesne, et al. (1988). "Hypoplasia of cerebellar vermal lobules VI and VII in autism." N Engl J Med 318(21): 1349-1354.

28. Jeannerod, M. (1984). "The timing of natural prehension movements." J Mot Behav 16(3): 235- 254.

29. Mostofsky, S. H., R. Bunoski, et al. (2004). "Children with autism adapt normally during a catching task requiring the cerebellum." Neurocase 10(1): 60-64.

30. Nowak, D. A., J. Hermsdorfer, et al. (2004). "Predictive and reactive finger force control during catching in cerebellar degeneration." Cerebellum 3(4): 227-235.

31. Gowen, E. and R. C. Miall (2007). "The cerebellum and motor dysfunction in neuropsychiatric disorders." Cerebellum 6(3): 268-279.

32. Timmann, D. and I. Daum (2007). "Cerebellar contributions to cognitive functions: A progress report after two decades of research." Cerebellum 6(3): 159-162.

33. Ouchi, Y., H. Okada, et al. (1999). "Brain activation during maintenance of standing postures in humans." Brain 122 ( Pt 2): 329-338.

34. McAlonan, G. M., E. Daly, et al. (2002). "Brain anatomy and sensorimotor gating in Asperger's syndrome." Brain 125(Pt 7): 1594-1606.

35. McAlonan, G. M. (2004). "Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autism." Brain 128(2): 268-276.

36. Grafton, S. T., A. H. Fagg, et al. (1996). "Functional anatomy of pointing and grasping in humans." Cerebral cortex 6(2): 226-237.

37. Miall, R. C. and P. Silburn (1997). "A study of motor performance and motor learning in episodic ataxia." Neuroreport 8(9-10): 2159-2164.

38. Mari, M., U. Castiello, et al. (2003). "The reach-to-grasp movement in children with autism spectrum disorder." Philos Trans R Soc Lond B Biol Sci 358(1430): 393-403.

39. Begliomini, C., M. B. Wall, et al. (2007). "Differential cortical activity for precision and whole- hand visually guided grasping in humans." Eur J Neurosci 25(4): 1245-1252.

40. Klin, A., F. R. Volkmar, et al. (1995). "Validity and neuropsychological characterization of Asperger syndrome: convergence with nonverbal learning disabilities syndrome." J Child Psychol Psychiatry 36(7): 1127-1140.

41. Rinehart, N. J., B. J. Tonge, et al. (2006). "Gait function in newly diagnosed children with autism: Cerebellar and basal ganglia related motor disorder." Dev Med Child Neurol 48(10): 819-824.

42. Shadmehr, R. and H. H. Holcomb (1997). "Neural Correlates of Motor Memory Consolidation." Science 277(5327): 821-825.

43. Blakemore, S. J., D. Wolpert, et al. (2000). "Why can't you tickle yourself?" Neuroreport 11(11): R11-16.

44. Diedrichsen, J. (2004). "Cerebellar Involvement in Anticipating the Consequences of Self- Produced Actions During Bimanual Movements." J Neurophysiol 93(2): 801-812.

45. Küper, M., B. Brandauer, et al. (2011). "Impaired prehension is associated with lesions of the superior and inferior hand representation within the human cerebellum." J Neurophysiol 105(5): 2018-2029.

46. Monzee, J. and A. M. Smith (2004). "Responses of cerebellar interpositus neurons to predictable perturbations applied to an object held in a precision grip." J Neurophysiol 91(3): 1230-1239.

47. Minshew, N. J., K. Sung, et al. (2004). "Underdevelopment of the postural control system in autism." Neurology 63(11): 2056-2061.

48. Courchesne, E., O. Saitoh, et al. (1994). "Abnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: identification of hypoplastic and hyperplastic subgroups with MR imaging." AJR. American journal of roentgenology 162(1): 123-130.

49. Akshoomoff, N. A. and E. Courchesne (1994). "ERP Evidence for a Shifting Attention Deficit in Patients with Damage to the Cerebellum." J Cogn Neurosci 6(4): 388-399.

50. Griebling, J., N. J. Minshew, et al. (2010). "Dorsolateral prefrontal cortex magnetic resonance imaging measurements and cognitive performance in autism." Journal of child neurology 25(7): 856-863.

51. Gribble, P. L. and D. J. Ostry (1999). "Compensation for interaction torques during single-and multijoint limb movement." J Neurophysiol 82(5): 2310-2326.

52. Abell, F., M. Krams, et al. (1999). "The neuroanatomy of autism: a voxel-based whole brain analysis of structural scans." Neuroreport 10(8): 1647-1651.

53. Muller, F. and J. Dichgans (1994). "Dyscoordination of pinch and lift forces during grasp in patients with cerebellar lesions." Exp Brain Res 101(3): 485-492.

54. Paulignan, Y., V. G. Frak, et al. (1997). "Influence of object position and size on human prehension movements." Exp Brain Res 114(2): 226-234.

55. Castiello, U., K. Bennett, et al. (1999). "The reach-to-grasp movement in Parkinson's disease: response to a simultaneous perturbation of object position and object size." Exp Brain Res 125(4): 453-462.

56. Rinehart, N. J., M. A. Bellgrove, et al. (2006). "An examination of movement kinematics in young people with high-functioning autism and Asperger's disorder: further evidence for a motor planning deficit." J Autism Dev Disord 36(6): 757-767.

57. Meindl, T., B. Schmid, et al. (2012). "Contribution of the Cerebellum to the Coupling of Grip Force and Pull Force During an Isometric Precision Grip Task." The Cerebellum 11(1): 167-180.

58. Nowak, D. A., H. Topka, et al. (2007). "The role of the cerebellum for predictive control of grasping." Cerebellum 6(1): 7-17.

59. Gidley Larson, J. C., A. J. Bastian, et al. (2008). "Acquisition of internal models of motor tasks in children with autism." Brain 131(Pt 11): 2894-2903.

60. Sivaswamy, L., A. Kumar, et al. (2010). "A diffusion tensor imaging study of the cerebellar pathways in children with autism spectrum disorder." Journal of child neurology 25(10): 1223-1231.

61. Nowak, D. A. and J. Hermsdorfer (2004). "[Analysis of grip force during object manipulation. Method for the objective measurement of physiological normal and impaired hand function]." Der Nervenarzt 75(8): 725-733.

62. Kudoh, N., M. Hattori, et al. (1997). "An analysis of spatiotemporal variability during prehension movements: effects of object size and distance." Exp Brain Res 117(3): 457- 464.

63. Desmurget, M., C. Prablanc, et al. (1999). "Are Reaching Movements Planned to be Straight and Invariant in the Extrinsic Space? Kinematic Comparison Between Compliant and Unconstrained Motions." The Quarterly Journal of Experimental Psychology Section A 52(4): 981-1020.

64. Szatmari, P., L. Tuff, et al. (1990). "Asperger's syndrome and autism: neurocognitive aspects." J Am Acad Child Adolesc Psychiatry 29(1): 130-136.

65. Wing, L. (1981). "Asperger syndrome: a clinical account." Psychological Medicine 11: 115-129.

66. Gilbert, S. J., G. Bird, et al. (2008). "Atypical recruitment of medial prefrontal cortex in autism spectrum disorders: an fMRI study of two executive function tasks." Neuropsychologia 46(9): 2281-2291.

67. Williams, R. S., S. L. Hauser, et al. (1980). "Autism and mental retardation: neuropathologic studies performed in four retarded persons with autistic behavior." Arch Neurol 37(12): 749-753.

68. Gowen, E. and R. C. Miall (2005). "Behavioural aspects of cerebellar function in adults with Asperger syndrome." Cerebellum 4(4): 279-289.

69. Jahn, K., A. Deutschländer, et al. (2004). "Brain activation patterns during imagined stance and locomotion in functional magnetic resonance imaging." Neuroimage 22(4): 1722-1731.

70. Nickl-Jockschat, T., U. Habel, et al. (2012). "Brain structure anomalies in autism spectrum disorder--a meta-analysis of VBM studies using anatomic likelihood estimation." Human brain mapping 33(6): 1470-1489.

71. Blakemore, S. J., D. M. Wolpert, et al. (1998). "Central cancellation of self-produced tickle sensation." Nat Neurosci 1(7): 635-640.

72. Bastian, A. J., T. A. Martin, et al. (1996). "Cerebellar ataxia: abnormal control of interaction torques across multiple joints." J Neurophysiol 76(1): 492-509.

73. Whitney, E. R., T. L. Kemper, et al. (2008). "Cerebellar Purkinje Cells are Reduced in a Subpopulation of Autistic Brains: A Stereological Experiment Using Calbindin-D28k." Cerebellum 7(3): 406-416.

74. Coltz, J. D., M. T. Johnson, et al. (1999). "Cerebellar Purkinje cell simple spike discharge encodes movement velocity in primates during visuomotor arm tracking." J Neurosci 19(5): 1782-1803.

75. Rand, M. K., A. L. Smiley-Oyen, et al. (2006). "Control of aperture closure during reach-to-grasp movements in parkinson's disease." Exp Brain Res 168(1-2): 131-142.

76. Haggard, P., R. C. Miall, et al. (1995). "Damage to cerebellocortical pathways after closed head injury: a behavioural and magnetic resonance imaging study." Journal of neurology, neurosurgery, and psychiatry 58(4): 433-438.

77. Mostofsky, S. H., S. K. Powell, et al. (2009). "Decreased connectivity and cerebellar activity in autism during motor task performance." Brain 132(9): 2413-2425.

78. Nowak, D. A., D. Timmann, et al. (2007). "Dexterity in cerebellar agenesis." Neuropsychologia 45(4): 696-703.

79. Nowak, D. A., C. Grefkes, et al. (2007). "Dexterity is impaired at both hands following unilateral subcortical middle cerebral artery stroke." European Journal of Neuroscience 25(10): 3173-3184.

80. American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders: DSM-5. Washington, D.C, American Psychiatric Association.

81. American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders : DSM-IV-TR. Washington, DC, American Psychiatric Association: xxxvii, 943.

82. Nayate, A., B. J. Tonge, et al. (2012). "Differentiation of high-functioning autism and Asperger's disorder based on neuromotor behaviour." J Autism Dev Disord 42(5): 707-717.

83. David, N., A. Gawronski, et al. (2007). "Dissociation Between Key Processes of Social Cognition in Autism: Impaired Mentalizing But Intact Sense of Agency." J Autism Dev Disord 38(4): 593-605.

84. Fombonne, E. and L. Tidmarsh (2003). "Epidemiologic data on Asperger disorder." Child Adolesc Psychiatr Clin N Am 12(1): 15-21.

85. Boecker, H., A. Lee, et al. (2005). "Force level independent representations of predictive grip force–load force coupling: A PET activation study." Neuroimage 25(1): 243-252.

86. Wolpert, D. M. and R. C. Miall (1996). "Forward Models for Physiological Motor Control." Neural Netw 9(8): 1265-1279.

87. Schoch, B., A. Dimitrova, et al. (2006). "Functional localization in the human cerebellum based on voxelwise statistical analysis: a study of 90 patients." Neuroimage 30(1): 36-51.

88. Vilensky, J. A., A. R. Damasio, et al. (1981). "Gait disturbances in patients with autistic behavior: a preliminary study." Arch Neurol 38(10): 646-649.

89. Hejdukova, B., N. Hosseini, et al. (2002). "Grip and load force coordination during a manual transport movement: findings in healthy participants." Motor Control 6(3): 282-293.

90. Nowak, D. A., J. Hermsdorfer, et al. (2002). "Grip and load force coupling during discrete vertical arm movements with a grasped object in cerebellar atrophy." Exp Brain Res 145(1): 28-39.

91. Tewes, U. (1991). Hamburg-Wechsler Intelligenztest fuer Erwachsene, Revision 1991. Bern, Huber.

92. Bauman, M. and T. L. Kemper (1985). "Histoanatomic observations of the brain in early infantile autism." Neurology 35(6): 866-874.

93. Imamizu, H., S. Miyauchi, et al. (2000). "Human cerebellar activity reflecting an acquired internal model of a new tool." Nature 403(6766): 192-195.

94. Nowak, D. A., J. Hermsdörfer, et al. (2005). "Impaired generalization of weight-related information during grasping in cerebellar degeneration." Neuropsychologia 43(1): 20- 27.

95. Courchesne, E., J. Townsend, et al. (1994). "Impairment in shifting attention in autistic and cerebellar patients." Behavioral neuroscience 108(5): 848-865.

96. van Donkelaar, P. and R. G. Lee (1994). "Interactions between the eye and hand motor systems: disruptions due to cerebellar dysfunction." J Neurophysiol 72(4): 1674-1685.

97. Kawato, M. (1999). "Internal models for motor control and trajectory planning." Curr Opin Neurobiol 9(6): 718-727.

98. Wolpert, D. M., R. C. Miall, et al. (1998). "Internal models in the cerebellum." Trends in Cognitive Sciences 2(9): 338-347.

99. World Health Organization (1990). International statistical classification of diseases and related health problems (ICD-10). Geneva, World Health Organization (WHO).

100. Ghaziuddin, M., E. Butler, et al. (1994). "Is clumsiness a marker for Asperger syndrome?" J Intellect Disabil Res 38 ( Pt 5): 519-527.

101. Hallett, M., M. K. Lebiedowska, et al. (1993). "Locomotion of autistic adults." Arch Neurol 50(12): 1304-1308.

102. Ritvo, E. R., B. J. Freeman, et al. (1986). "Lower Purkinje cell counts in the cerebella of four autistic subjects: initial findings of the UCLA-NSAC Autopsy Research Report." Am J Psychiatry 143(7): 862-866.

103. Nitschke, M. F., G. Stavrou, et al. (2003). "Modulation of cerebellar activation by predictive and non-predictive sequential finger movements." Cerebellum 2(3): 233-240.

104. Schmitz, C., J. Martineau, et al. (2003). "Motor control and children with autism: deficit of anticipatory function?" Neurosci Lett 348(1): 17-20.

105. Fournier, K. A., C. J. Hass, et al. (2010). "Motor coordination in autism spectrum disorders: a synthesis and meta-analysis." J Autism Dev Disord 40(10): 1227-1240.

106. Weimer, A. K., A. M. Schatz, et al. (2001). ""Motor" impairment in Asperger syndrome: evidence for a deficit in proprioception." J Dev Behav Pediatr 22(2): 92-101.

107. Hardan, A. Y., M. Kilpatrick, et al. (2003). "Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism." Journal of child neurology 18(5): 317-324.

108. Wolpert, D. M. and M. Kawato (1998). "Multiple paired forward and inverse models for motor control." Neural Netw 11(7-8): 1317-1329.

109. Desmurget, M. and C. Prablanc (1997). "Postural control of three-dimensional prehension movements." J Neurophysiol 77(1): 452-464.

110. Molloy, C. A., K. N. Dietrich, et al. (2003). "Postural stability in children with autism spectrum disorder." J Autism Dev Disord 33(6): 643-652.

111. Fellows, S. J., J. Noth, et al. (1998). "Precision grip and Parkinson's disease." Brain 121(9): 1771- 1784.

112. Johansson, R. S. and G. Westling (1988). "Programmed and triggered actions to rapid load changes during precision grip." Experimental brain research. Experimentelle Hirnforschung. Experimentation cerebrale 71(1): 72-86.

113. Espinoza, E. and A. M. Smith (1990). "Purkinje cell simple spike activity during grasping and lifting objects of different textures and weights." J Neurophysiol 64(3): 698-714.

114. Mason, C. R., C. M. Hendrix, et al. (2006). "Purkinje cells signal hand shape and grasp force during reach-to-grasp in the monkey." J Neurophysiol 95(1): 144-158.

115. Dugas, C. and A. M. Smith (1992). "Responses of cerebellar Purkinje cells to slip of a hand-held object." J Neurophysiol 67(3): 483-495.

116. Johansson, R. S. and G. Westling (1984). "Roles of glabrous skin receptors and sensorimotor memory in automatic control of precision grip when lifting rougher or more slippery objects." Exp Brain Res 56(3): 550-564.

117. Paulignan, Y., C. MacKenzie, et al. (1991). "Selective perturbation of visual input during prehension movements. 1. The effects of changing object position." Exp Brain Res 83(3): 502-512.

118. Spraker, M. B., D. M. Corcos, et al. (2012). "Specific cerebellar regions are related to force amplitude and rate of force development." Neuroimage 59(2): 1647-1656.

119. Gomi, H., M. Shidara, et al. (1998). "Temporal firing patterns of Purkinje cells in the cerebellar ventral paraflocculus during ocular following responses in monkeys I. Simple spikes." J Neurophysiol 80(2): 818-831.

120. Oldfield, R. C. (1971). "The assessment and analysis of handedness: the Edinburgh inventory." Neuropsychologia 9(1): 97-113.

121. Baron-Cohen, S., S. Wheelwright, et al. (2001). "The autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians." J Autism Dev Disord 31(1): 5-17.

122. Miall, R. C., G. Z. Reckess, et al. (2001). "The cerebellum coordinates eye and hand tracking movements." Nat Neurosci 4(6): 638-644.

123. Blakemore, S. J., C. D. Frith, et al. (2001). "The cerebellum is involved in predicting the sensory consequences of action." Neuroreport 12(9): 1879-1884.

124. Kemper, T. L. and M. L. Bauman (1993). "The contribution of neuropathologic studies to the understanding of autism." Neurologic clinics 11(1): 175-187.

125. Nowak, D. A., J. Hermsdorfer, et al. (2001). "The effects of digital anaesthesia on predictive grip force adjustments during vertical movements of a grasped object." Eur J Neurosci 14(4): 756-762.

126. Ehlers, S. and C. Gillberg (1993). "The epidemiology of Asperger syndrome. A total population study." J Child Psychol Psychiatry 34(8): 1327-1350.

127. Flanagan, J. R. and A. M. Wing (1997). "The role of internal models in motion planning and control: evidence from grip force adjustments during movements of hand-held loads." J Neurosci 17(4): 1519-1528.

128. Bootsma, R. J., R. G. Marteniuk, et al. (1994). "The speed-accuracy trade-off in manual prehension: effects of movement amplitude, object size and object width on kinematic characteristics." Exp Brain Res 98(3): 535-541.

129. Holmes, G. (1917). "The symptoms of acute cerebellar injuries due to gunshot injuries." Brain 40(4): 461-535.

130. Silk, T. J., N. Rinehart, et al. (2006). "Visuospatial processing and the function of prefrontal- parietal networks in autism spectrum disorders: a functional MRI study." Am J Psychiatry 163(8): 1440-1443.

131. Timmann, D. (1997). Zur Bedeutung des menschlichen Kleinhirns für einfache und komplexe motorische Lernvorgänge. Habilitation Habilitationsschrift, Universität Essen.

132. Ghaziuddin, M. and E. Butler (1998). "Clumsiness in autism and Asperger syndrome: a further report." J Intellect Disabil Res 42 ( Pt 1): 43-48.

133. Baron-Cohen, S., S. Wheelwright, et al. (2001). "The "Reading the Mind in the Eyes" Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism." J Child Psychol Psychiatry 42(2): 241-251.

134. Gentilucci, M., U. Castiello, et al. (1991). "Influence of different types of grasping on the transport component of prehension movements." Neuropsychologia 29(5): 361-378.

135. Flanagan, J. R., J. Tresilian, et al. (1993). "Coupling of grip force and load force during arm movements with grasped objects." Neurosci Lett 152(1–2): 53-56.

136. Schmitz, N., K. Rubia, et al. (2006). "Neural correlates of executive function in autistic spectrum disorders." Biol Psychiatry 59(1): 7-16.

137. Sailer, U., T. Eggert, et al. (2005). "Impaired temporal prediction and eye-hand coordination in patients with cerebellar lesions." Behav Brain Res 160(1): 72-87.

138. Bursztyn, L. L. C. D., G. Ganesh, et al. (2006). "Neural Correlates of Internal-Model Loading." Current Biology 16(24): 2440-2445.

139. Catani, M., D. K. Jones, et al. (2008). "Altered cerebellar feedback projections in Asperger syndrome." Neuroimage 41(4): 1184-1191.

140. Maltz, A. and T. E. Goldberg (1982). "Neuropsychological recovery following acute cerebellar ataxia." J Clin Neuropsychol 4(4): 297-305.