Synthesis, Identification, Kinetic, and Structural Characterization of Inhibitors of the Aspartic Proteases HTLV-1 Protease and Endothiapepsin

Synthesis, Identification, Kinetic, and Structural Characterization of Inhibitors of the Aspartic Proteases HTLV-1 Protease and Endothiapepsin

This thesis focuses on the identification and synthesis as well as kinetic and structural characterization of non-peptidic small molecule inhibitors of the two aspartic proteases HTLV-1 protease (HTLV-1 PR) and endothiapepsin. The HTLV-1 PR, a promising target for the treatment of viral infections...

Fuld beskrivelse

Gespeichert in:
Bibliografiske detaljer
Hovedforfatter: Kuhnert, Maren Sophia
Andre forfattere: Diederich, Wibke (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2015
Fag:
Wirkstoffdesign
aspartic proteases
enzyme inhibitor
Inhibitor
Enzym
Proteinkristallographie
drug design
X-ray crystallography
Medizin
Aspartylproteasen
Indinavir
Proteasen
HTLV-1-Proteaseinhibitor
Medical sciences Medicine
Online adgang:PDF-Volltext
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
No citations were found for this record.

Lignende værker