Synthesis, Identification, Kinetic, and Structural Characterization of Inhibitors of the Aspartic Proteases HTLV-1 Protease and Endothiapepsin
This thesis focuses on the identification and synthesis as well as kinetic and structural characterization of non-peptidic small molecule inhibitors of the two aspartic proteases HTLV-1 protease (HTLV-1 PR) and endothiapepsin. The HTLV-1 PR, a promising target for the treatment of viral infections...
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