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An extracellular drug binding site of potassium channels THIK-1 and THIK-2
Background: THIK-1, THIK-2 and TREK-1 and all belong to family of two-pore-domain potassium channel (K2P channels). THIK-2 was until recently regarded as ‘silent’ potassium channels. 3-isobutyl-1-methylxanthine (IBMX) is normally used as inhibitor of phosphodiesterase, resulting in an increase of cA...
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| Format: | Dissertation |
| Sprache: | Englisch |
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Philipps-Universität Marburg
2015
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