Aetiopathogenesis and Phenomenology of Medically Unexplained Conditions

Functional somatic syndromes (FSS) are characterised by the presence of somatic symptoms and the absence of any demonstrable abnormalities of organ structure or function that would allow an attribution to a conventionally defined medical disease. There are numerous case definitions for different FSS...

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Bibliographic Details
Main Author: Fischer, Susanne
Contributors: Nater, Urs (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2015
Psychologie
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28. La Marca), University of Zurich, Zurich, Switzerland Clinical experience Feb. 2011-Dec. 2014 Therapist, Outpatient Clinic for Psychological Interventions (Prof. W. Rief), Marburg, Germany Sept.-Dec. 2009


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34. Doerr, J. M., Strahler, J., Fischer, S. & Nater, U. M. (2014). Acute stress influences momentary pain in women with fibromyalgia. International Journal of Behavioral Medicine, 21(Suppl. 1), S134.


35. Ad hoc reviewer for scientific journals International Journal of Behavioral Medicine Journal of Psychosomatic Research Peer-reviewed journal articles


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38. Markert, C., Doerr, J.M., Fischer, S., Tepe, A., Sanchez, L. & Nater, U.M. (2013). Beeinflusst Stress das alltägliche Schmerzerleben von Frauen mit Fibromyalgie [Does stress have an impact on daily pain experiences in women with fibromyalgia]? Verhaltenstherapie & Verhaltensmedizin, 34(Suppl. 1), 19.


39. Strahler, J., Fischer, S., Nater, U. M., Ehlert, U. & Gaab, J. (2012). Catecholaminergic responses to the insulin tolerance test in chronic fatigue syndrome. Psychosomatic Medicine, 74(3), A-84.


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41. Klaus, K., Fischer, S., Doerr, J. M., Nater, U. M. & Mewes, R. (submitted). Classifying fibromyalgia as a psychiatric disorder? An ambulatory assessment study. Journal of Pain.


42. Doerr, J. M., Fischer, S., Strahler, J. & Nater, U. M. (2014). Der Effekt von akutem Stress im Alltag auf das Schmerzerleben bei Frauen mit Fibromyalgie [The effect of acute stress in everday life on pain experiences in women with fibromyalgia]. Poster presented at the 32nd Symposium of the Division of Clinical Psychology and Psychotherapy of the German Psychological Society (DGPs), Brunswick, Germany.


43. Fischer, S., Strahler, J. & Nater, U. M. (2012). Die Rolle von Stress beim chronischen Erschöpfungssyndrom [The role of stress in chronic fatigue syndrome]. Talk given at the 27th Annual Meeting of the German Society of Behavior Therapy (DGVT), Berlin, Germany.


44. Fischer, S., Markert, C., Strahler, J. & Nater, U. M. (2013). Differentielle Stressreaktivität bei funktionellen somatischen Syndromen [Differential stress reactivity in functional somatic syndromes]. Talk given at the Young Scientist Retreat of the German Society for Psychophysiology and its Application (DGPA) and the Division of Biological Psychology and Neuropsychology of the German Psychological Society (DGPs), Berlin, Germany.


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48. Jan. 2015-present Visiting Researcher, Psychological Medicine (Prof. A. Cleare), King's College, London, United Kingdom Feb. 2011-Dec. 2014 Research Fellow, Clinical Biopsychology (Prof. U. M. Nater), University of Marburg, Marburg, Germany Oct. 2012-Sept. 2014


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50. Strahler, J.*, Fischer, S.*, Nater, U.M., Ehlert, U. & Gaab, J. (2013). Norepinephrine and epinephrine responses to physiological and pharmacological stimulation in chronic fatigue syndrome. Biological Psychology, 94(1), 160-6.


51. Fischer, S., Ehlert, U. & Nater, U. M. (2012). Overlap of functional somatic syndromes -findings from a non-clinical sample. International Journal of Behavioral Medicine, 19(Suppl. 1), 53.


52. Poster presented at the 15th Annual Meeting of the German Society for Psychological Pain Therapy and Research, Marburg, Germany.


53. Poster presented at the 32nd Symposium of the Division of Clinical Psychology and Psychotherapy of the German Psychological Society (DGPs), Brunswick, Germany.


54. Fischer, S., Gaab, J., Ehlert, U. & Nater, U. M. (2011). Prevalence of functional somatic syndromes in an apparently healthy population. Psychosomatic Medicine, 73(1), 32.


55. Fischer, S., Mewes, R., Dieterich, L., Öczan, O. & Nater, U.M. (2013). Psychobiologische Validierung eines Diskriminierungsparadigmas im Labor [Psychobiological validation of a discrimination paradigm in the laboratory]. Verhaltenstherapie & Verhaltensmedizin, 34(Suppl. 1), 11-2.


56. Klaus, K., Doerr, J. M., Fischer, S., Nater, U. M. & Mewes, R. (2014). Psychologische Somatisierungssymptome bei Patientinnen mit Fibromyalgie: Eine ambulante Assessement-Studie [Psychological symptoms of somatization in fibromyalgia patientes: an ambulatory assessment study].


57. Strahler, J., Fischer, S., Doerr, J.M. & Nater, U.M. (2014). Relationships between momentary stress, neuroendocrine stress markers, and symptoms in patients with fibromyalgia. Psychosomatic Medicine, 76(3), A-121.


58. Running head: The latent structure and correlates of somatic symptom distress 17


59. *Shared first authorship Book chapters


60. Markert, C., Fischer, S., Ehlert, U. & Nater, U. M. (2012). Stress and functional gastrointestinal disorders in a non-clinical sample. International Journal of Behavioral Medicine, 19(Suppl. 1), 54-5.


61. Fischer, S., Ehlert, U. & Nater, U. M. (2012). Stress as a risk factor in chronic fatigue -a prospective study in a Swiss student population. Psychosomatic Medicine, 74(3), A-30-31.


62. Markert, C., Fischer, S. & Nater, U. M. (2014). Stress is associated with diminished sexual interest in a Swiss student population. International Journal of Behavioral Medicine, 21(Suppl. 1), S179.


63. Doerr, J.M.*, Fischer, S.*, Strahler, J. & Nater, U.M. (2013). Stress und Schmerz: Eine psychobiologische Untersuchung im Alltag von Patientinnen mit Fibromyalgie [Stress and pain: A psychobiological approach in the daily life of fibromyalgia patients]. Poster presented at the 15th Annual Meeting of the German Society for Psychological Pain Therapy and Research, Marburg, Germany.


64. Markert, C., Fischer, S., Nater, U.M. (2014). Stress und vermindertes sexuelles Verlangen bei Schweizer Studierenden [Stress and diminished sexual desire in a Swiss student population]. Poster presented at the 32nd Symposium of the Division of Clinical Psychology and Psychotherapy of the German Psychological Society (DGPs), Brunswick, Germany.


65. Cantonal Psychiatric Clinic, Liestal, Switzerland Teaching experience Feb. 2011-present Co-mentoring of six master theses Feb. 2011-Dec. 2014 Substitutions in courses on depression, post-traumatic stress disorder, stress, fatigue, and sexual dysfunction disorders Apr.-Jul. 2013 Lectureship in anxiety disorders Awards and Scholarships Early Postdoc.Mobility Scholarship, Swiss National Science Foundation, Jan. 2015-Jun. 2016


66. MSc in Psychology Department of Psychology, Clinical Psychology and Psychotherapy, University of Zurich, Zurich, Switzerland Title of master thesis: " The role of stress in functional somatic symptoms " (Supervisors: Prof. U. Ehlert, Prof. U. M. Nater)


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68. Fischer, S. & Nater, U. M. (2013). Ätiopathogenetische Faktoren bei funktionellen somatischen Syndromen [Etiopathogenetic factors in functional somatic syndromes]. Verhaltenstherapie & Verhaltensmedizin, 34(4), 419-43.


69. Strahler, J., Fischer, S. & Kirschbaum, C. (2012). Vital exhaustion is differentially related to daily salivary cortisol in older men and women. Psychosomatic Medicine, 74(3), A-30.


70. Brunner, M., Nagy, G., & Wilhelm, O. (2012). A tutorial on hierarchically structured constructs. Journal of Personality, 80, 796–846.


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73. Fink P, Steen Hansen M, Sondergaard L. Somatoform disorders among first-time referrals to a neurology service. Psychosomatics. 2005;46:540–8.


74. Fischer, S. & Nater, U. M. (2014). Functional somatic syndromes: Asking about exclusionary medical conditions results in decreased prevalence and overlap rates. BMC Public Health, 14(1), 1034.


75. Nater, U. M., Fischer, S. & Ehlert, U. (2011). Stress as a pathophysiological factor in functional somatic syndromes. Current Psychiatry Reviews, 7(2), 152-69.


76. Brown, R. J. (2004). Psychological mechanisms of medically unexplained symptoms: an integrative conceptual model. Psychological Bulletin, 130, 793–812.


77. Fischer, S., Lemmer, G., Gollwitzer, M. & Nater, U. M. (2014). Stress and resilience in functional somatic syndromes – a structural equation modeling approach. PLoS One, 9(11), e111214.


78. Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16, 606–613.


79. Harris AM, Orav EJ, Bates DW, Barsky AJ. Somatization increases disability independent of comorbidity. J Gen Intern Med. 2009;24:155–61.


80. Körber, S., Frieser, D., Steinbrecher, N., & Hiller, W. (2011). Classification characteristics of the Patient Health Questionnaire-15 for screening somatoform disorders in a primary care setting. Journal of Psychosomatic Research, 71(3), 142–147.


81. Wessely S, Nimnuan C, Sharpe M: Functional somatic syndromes: one or many? Lancet 1999, 354:936–939.


82. McBeth J, Jones K: Epidemiology of chronic musculoskeletal pain. Best Pract Res Clin Rheumatol 2007, 21:403–425.


83. Jasper, F., Nater, U. M., Hiller, W., Ehlert, U., Fischer, S., & Witthöft, M. (2013). Rasch scalability of the somatosensory amplification scale: A mixture distribution approach. Journal of Psychosomatic Research, 74(6), 469–478.


84. Barsky, A. J., & Borus, J. F. (1999). Functional somatic syndromes. Annals of Internal Medicine, 130(11), 910–921.


85. Skoluda, S., Strahler, J., Schlotz, W., Niederberger, L., Marques, S., Fischer, S., Thoma, M. V., Spoerri, C., Ehlert, U. & Nater, U. M. (2015). Intra-individual psychological and physiological responses to acute laboratory stressors of different intensity. Psychoneuroendocrinology, 51, 227-36.


86. Nimnuan C, Hotopf M, Wessely S. Medically unexplained symp- toms: an epidemiological study in seven specialities. J Psychosom Res. 2001;51:361–7.


87. Strahler, J., Fischer, S., Nater, U. M., Ehlert, U. & Gaab, J. (2012). Epinephrine and norepinephrine responses to physiological and pharmacological stimulation in chronic fatigue syndrome. International Journal of Behavioral Medicine, 19(Suppl. 1), 118-9.


88. Fischer S, Gaab J, Ehlert U, Nater UM: Prevalence, overlap, and predictors of functional somatic syndromes in a student sample. Int J Behav Med 2013, 20:184–193.


89. Fischer, S., Doerr, J. M., Strahler, J., Mewes, R. & Nater, U. M. (ready to be submitted). Stress exacerbates pain in the everyday lives of women with fibromyalgia – the role of cortisol and alpha- amylase.