Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Lasso peptides are a class of natural products that belong to the family of ribosomally‑assembled and posttranslationally‑modified peptides. They are defined by an unique structural motif referred to as the so‑called lariat knot, whose name is derived from the fact that this topology is reminiscent...

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Bibliographic Details
Main Author: Hegemann, Julian David
Contributors: Marahiel, Mohamed A. (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2014
Online Access:PDF Full Text
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