Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Lasso peptides are a class of natural products that belong to the family of ribosomally‑assembled and posttranslationally‑modified peptides. They are defined by an unique structural motif referred to as the so‑called lariat knot, whose name is derived from the fact that this topology is reminiscent...

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Bibliografische gegevens
Hoofdauteur: Hegemann, Julian David
Andere auteurs: Marahiel, Mohamed A. (Prof. Dr.) (Thesis begeleider)
Formaat: Dissertation
Taal:Engels
Gepubliceerd in: Philipps-Universität Marburg 2014
Onderwerpen:
Lassopeptide
Epitope Grafting
Strukturaufklärung
Naturstoffchemie
RIPPs
epitope grafting
Biosynthese
lasso peptide
ribosomal synthetisierte Naturstoffe
ribosomally-assembled natural products
Naturstoff
Wirkstoffentwicklung
Chemie
Peptide
drug development
Biochemie
Chemistry & allied sciences
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