Anti-bacterial and Anti-adhesive Nanostructured Coatings for Improved Implant Biocompatibility

In this thesis, new coatings against bacterial adhesion and protein adsorptionwere developed, characterized and their effectiveness against bacterial adhesion and protein adsorption was investigated. Two strategies were followed to resist the bacterial adhesion. The first one is based on designing o...

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Bibliographic Details
Main Author: Dayyoub, Eyas
Contributors: Bakowsky, Udo (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2012
Pharmazeutische Technologie und Biopharmazie
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Summary:In this thesis, new coatings against bacterial adhesion and protein adsorptionwere developed, characterized and their effectiveness against bacterial adhesion and protein adsorption was investigated. Two strategies were followed to resist the bacterial adhesion. The first one is based on designing of high-ordered nanostructured polymer features while the second one concern with construction of polymer loaded with anti-bacterial agents. Reduction of protein adsorption is the second aim of this thesis. To achieve this goal, ultra-thin films with nano-scaled topography were manufactured.
DOI:https://doi.org/10.17192/z2014.0289