Studien zur Biosynthese von Sactipeptiden: Charakterisierung der an der Thioetherbrückenbildung beteiligten Radical SAM Enzyme AlbA und SkfB

Sactipeptide sind eine neue Klasse ribosomal synthetisierter, meist bioaktiver Peptide, die aus 26 bis 35 proteinogenen Aminosäuren bestehen. Ihr charakteristisches Merkmal ist eine Thio-etherbindung, die das Schwefelatom einer Cysteingruppe mit dem α-Kohlenstoffatom einer Ak-zeptoraminosäure verknü...

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Bibliographic Details
Main Author: Flühe, Leif
Contributors: Marahiel, Mohamed A. (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2014
Chemie
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