The analysis of programmed cell death and sporulation in Myxococcus xanthus developmental program

Coordinated behavior and the differentiation of genetic identical cells into distinct cell types have been described for several prokaryotic model species among which is Myxococcus xanthus. Upon nutrient starvation, M. xanthus undergoes a complex developmental life cycle, in which vegetative cells d...

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Bibliographic Details
Main Author: Holkenbrink, Carina
Contributors: Higgs, Penelope (Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2014
Biologie
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Summary:Coordinated behavior and the differentiation of genetic identical cells into distinct cell types have been described for several prokaryotic model species among which is Myxococcus xanthus. Upon nutrient starvation, M. xanthus undergoes a complex developmental life cycle, in which vegetative cells differentiate into environmentally resistant spores. During the developmental program the cells enter one of at least three different cell fate paths, namely “programmed cell death”, sporulation and the differentiation into a persister-like state called “peripheral rods”. The first two cell fates, “cell lysis” and “sporulation”, were examined in the current study.
DOI:https://doi.org/10.17192/z2014.0063