Characterization of pathogenic auto-antibodies directed against desmoglein 3 and desmocollin 3 in sera of pemphigus patients.

Characterization of pathogenic auto-antibodies directed against desmoglein 3 and desmocollin 3 in sera of pemphigus patients.

Pemphigus vulgaris (PV) represents the most frequent clinical type of the pemphigus group of autoimmune bullous skin disorders. There is substantial evidence that blister formation in pemphigus patients is mediated by auto-antibodies (auto-Abs) targeted against certain desmosomal cadherins, namely d...

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Bibliographic Details
Main Author: Rafei-Shamsabadi, David Ali
Contributors: Eming, Rüdiger (PD Dr. med.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2013
Subjects:
antibodies
Medizin
desmoglein 3
Pemphigus
pemphigus
pathogenic
Desmoglein 3
Pathogenität
desmocollin 3
Autoantikörper
Desmocollin 3
Medical sciences Medicine
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