Neue Gentargeting-Strategien auf Basis der RNA interference RNAi

RNA Interferenz ist ein natürlicher Prozess in eukaryoten Zellen, der zur spezifischen Herunterregulation der Genexpression (Gen-Silencing) führt. Der Mechanismus der RNAi wird durch 21 - 23 nt lange doppelsträngige RNA-Moleküle (siRNA) vermittelt, welche sequenzspezifisch den Abbau und die Degradat...

Ausführliche Beschreibung

Gespeichert in:
1. Verfasser: Werth, Stephanie
Beteiligte: Aigner, Achim (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Deutsch
Veröffentlicht: Philipps-Universität Marburg 2013
Pharmakologie und Toxikologie
Ausgabe:http://dx.doi.org/10.17192/z2013.0456
Schlagworte:
PTN
PEI
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