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Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation
The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2013
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| 在线阅读: | PDF-Volltext |
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