Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Bibliographic Details
Main Author: Milde, Markus
Contributors: Bünemann, Moritz (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2013
Pharmakologie und Toxikologie
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Call Number: urn:nbn:de:hebis:04-z2013-03902
Downloads: 33 (2020), 49 (2019), 49 (2018), 41 (2017), 56 (2016)
Publication Date: 2013-08-14
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2013/0390
https://doi.org/10.17192/z2013.0390