Biodegradable amphiphilic PEG-PCL-PEI triblock copolymers designed for the self-assembly of multifunctional gene carriers

Biodegradable amphiphilic PEG-PCL-PEI triblock copolymers designed for the self-assembly of multifunctional gene carriers

The great promise that gene therapy holds is the opportunity of directly introducing genetic material into cells for a causal therapy of yet incurable diseases. One promising way to achieve that goal is the usage of non-viral delivery vehicles, constructed from amphiphilic block copolymers. This...

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Bibliographic Details
Main Author: Endres, Thomas
Contributors: Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2012
Subjects:
Quantum dot
Fluoreszenz-Resonanz-Energie-Transfer
RNS-Interferenz
siRNA-Formulierung
Micelle
Self assembly
Gefriertrocknung
Copolymer
Quantenpunkt
Gentherapie
Lyophilisation
Cationic triblock copolymer
Naturwissenschaften
In vitro
In vivo
Natural sciences & mathematics
Online Access:PDF Full Text
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